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Rise above resistance

Trisenox uses a targeted, multifunctional approach to deliver high rates of remission with minimal chemotherapy-related side effects.

Trisenox (arsenic trioxide), injectable formulation, is indicated for the treatment of induction of remission and consolidation in patients with acute promyelocytic leukemia (APL) who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy, and whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression.

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Brand name: Trisenox
Generic name/category: arsenic trioxide, IARC Group 1 carcinogens, Antineoplastic drugs
Company: Cephalon Oncology
Country/Market: USA, North America
Indication(s)/use: acute promyelocytic leukemia (APL)
Target: Healthcare Professionals (HCP)
Tagline: Rise above resistance
Medium: Print ad
Size/duration: single-page
Publication/Aired: Blood – September 10, 2009
1 views
Sep 17, 2009

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Surviving an MI is death defying

Omacor can help improve your patients’ chance of survival post-MI.

Agency: Life Healthcare

Brand name: Omacor
Generic name/category: Omega-3-acid ethyl esters 90
Company: Solvay
Country/Market: UK, Europe
Indication(s)/use: Endogenous hypertriglyceridemia and adjuvant treatment in secondary prevention after myocardial infarction
Target: Consumers (DTC) / Healthcare Professionals (HCP) / Trade
Tagline: Optimise survival after MI
Publication: Magazine or other Month Year

For fast antifungal relief in athlete’s foot
Clinical improvement with relief of pruritus and other symptoms usually occurs within the first week of treatment.

Available in Cream 45 g tube and Lotion 60 mL bottle.

Ciclopirox olamine (also called Batrafen Loprox, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor.

In contrast to the azoles and other antimycotic drugs, the mechanism of action of ciclopirox is only poorly understood. However, loss of function of certain catalase and peroxidase enzymes has been implicated the mechanism of action, as well as various other components of cellular metabolism. In a study conducted to further elucidate ciclopirox’s mechanism, several Saccharomyces cerevisiae mutants were screened and tested. Results from interpretation of the effects of both the drug treatment and mutation suggested that ciclopirox may exert its effect by disrupting DNA repair, cell division signals and structures (mitotic spindles) as well as some elements of intracellular transport.

It acts by inhibiting the membrane transfer system by interrupting the Na+ K+ ATPase. It is currently being investigated as an alternative treatment to ketoconazole for seborrhoeic dermatitis as it suppresses growth of the yeast Malassezia furfur. Initial results show similar efficacy to ketoconazole with a relative increase in subjective symptom relief due to its inherent anti-inflammatory properties. – Wikipedia

Parkhurst Exchange April 2009