Archive for the ‘prodrugs’ tag

Plavix for PAD

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I have poor leg circulation

And I have a good reason to try to reduce the risk of heart attack or stroke that comes with it.

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Seldane TV commercial from 1990

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A series of people sneezing, one after the other in front of a background showing locations prone to trigger an allergic reaction. The background move as if they were on a train.

Sound effects of a train slowly fade in behind the sound of people sneezing. The train goes in a tunnel, everything turns black, then an alarm handle appears with the words “soulagement rapide” (rapid relief) written on it.

A hand pulls the handle letting a Seldane pack show up attached to the handle.

[Voice-over] Soulagez vos éternuements et vos yeux larmoyants tout en restant éveillés. Symptômes d’allergies? Seldane. A tchoo-tchoo puis c’est tout.
Relieve your sneezing and watery eyes while staying awake. Allergy symptoms? Seldane. Choo-choo and it’s over

Brand name: Seldane
Generic name/category: Terfenadine, Antihistamines, Withdrawn drugs, Prodrugs
Country/Market: Canada, North America
Indication(s)/use: Allergies, sneezing and watery eyes
Target: Consumers (DTC)
Tagline: A tchoo-tchoo puis c’est tout. – Choo-choo and it’s over
Medium: TV commercial
Size/duration: 30 seconds
Publication/Aired: 1990

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Toviaz for OAB

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thumb_Toviaz-ReadersDigest-Oct2009

If you can draw a map to every bathroom in town…

Today is the day to talk to your doctor about overactive bladder and Toviaz – a pill that comes with a plan

A pill for overactive bladder that comes with a plan

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AcipHex DTC print ad

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Acid reflux disease.
Burning. Bad taste in your throat. Belching.

Try AcipHex free for 2 weeks!
1-800-203-8672
TryAciphex.com/72

Brand name: AcipHex
Generic name/category: Rabeprazole, Prodrugs, Proton pump inhibitors, Benzimidazoles, Sulfoxides
Company: Eisai and PriCara
Country/Market: USA, North America
Indication(s)/use: Acid reflux disease
Target: Consumers (DTC) / Healthcare Professionals (HCP) / Trade
Tagline: Acid reflux disease. It’s got many faces.
Medium: Print ad
Size/duration: single-page
Publication/Aired: Ladies’ Home Journal – October 2009

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Toviaz – mosaic

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Now, a pill that comes with a plan.
Get the full picture in OAB care

Toviaz is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency

Fesoterodine (INN, brand name Toviaz) is an antimuscarinic drug developed by Schwarz Pharma AG to treat overactive bladder syndrome. It was approved by the European Medicines Agency in April 2007 and was approved by the US Food and Drug Administration on October 31, 2008.

Fesoterodine is a prodrug. It is broken down into its active metabolite, 5-hydroxymethyl tolterodine, by plasma esterases.

More on Wikipedia

Brand name: Toviaz
Generic name/category: Fesoterodine, Muscarinic antagonists, Prodrugs
Company: Pfizer
Country/Market: USA, North America
Indication(s)/use: Overactive bladder OAB
Target: Healthcare Professionals (HCP)
Tagline: Get the full picture in OAB care
Medium: Print ad
Size/duration: single-page
Publication/Aired: Urology Times – September 2009

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Sep 07, 2009

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Plavix – Living Proof

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Living proof

ACS – PAD – Stroke – PAD – ACS
4 large trials involving more than 81,000 patients.

Plavix ??? the only prescription antiplatelet with proven efficacy and a well-established safety profile in a broad range of patients.

Clopidogrel is an oral antiplatelet agent (thienopyridine class) to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix, by Sun Pharmaceuticals under the trade name Clopilet, by Ranbaxy Laboratories under the trade name Ceruvin. It works by irreversibly inhibiting a receptor called P2Y12. Adverse effects include hemorrhage.

More on Wikipedia

Brand name: Plavix
Generic name/category: Clopidogrel, Antiplatelet drugs, ADP receptor inhibitors, Thiophenes, Prodrugs
Company: Sanofi-Aventis and Bristol-Myers Squibb
Country/Market: USA, North America
Indication(s)/use: inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease
Target: Healthcare Professionals (HCP)
Tagline: Living Proof.
Medium: Print ad
Size/duration: double-page spread
Publication/Aired: The Journal of Invasive Cardiology – September 2009

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Sep 11, 2009

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