Like any intimate relationship, treatment for your vaginal discomfort after menopause doesn’t have to be superficial.

Premarin Vaginal Cream restores vaginal tissues after menopause, to help relieve symptoms and even painful intercourse.

Ask your healthcare professional about a cream that helps relieve and restore.

Get $15 off your prescription at www.premarinvaginalcream.com

Brand name: Premarin
Generic name/category: Conjugated estrogens
Company: Wyeth Pharmaceuticals
Country/Market: USA, North America
Indication(s)/use: atrophic vaginitis and kraurosis vulvae and the treatment of moderate to severe dyspareunia.
Target: Direct-to-consumer (DTC)
Tagline: Help relieve and restore what’s yours
Publication: People Magazine June 8 2009

To see all of this brand’s ads on AdPharm, click here

Show her what a difference a little bit of cream can make

Give her Premarin Vaginal Cream 0.5 g
Low-dose efficacy.
Low cream volume.
New endometrial safety data.

Brand name: Premarin
Generic name/category: Conjugated estrogens
Company: Wyeth Pharmaceuticals
Country/Market: USA, North America
Indication(s)/use: atrophic vaginitis and kraurosis vulvae and the treatment of moderate to severe dyspareunia.
Target: Healthcare Professionals (HCP)
Tagline: Relief–inside and out.
Publication: Contemporary ob/gyn June 2009

To see all of this brand’s ads on AdPharm, click here

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Estradiol (E2 or 17?-estradiol) (also oestradiol) is a sex hormone. Mislabelled the “female” hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

Estradiol, like other steroids, is derived from cholesterol. After side chain cleavage and utilizing the delta-5 pathway or the delta-4 pathway androstenedione is the key intermediary. A fraction of the androstenedione is converted to testosterone, which in turn undergoes conversion to estradiol by an enzyme called aromatase. Alternatively, androstenedione is “aromatized” to estrone, which is subsequently converted to estradiol.

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