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Only Yaz goes beyond birth control with 3 indications

For women who choose and OC for contraception, only Yaz with drsp/EE in a 24/4-day regimen provides:

1- 99% contraceptive efficacy when used correctly
2- Treatment of emotional and physical symptoms of premenstrual dysphoric disorder (PMDD)
3- Treatment of moderate acne

#1 branded OC among OB/GYNs

Brand name: [url=]Yasmin[/url]
Generic name/category: Drospirenone, contraceptive, Progestagens
Company: Bayer Healthcare
Country/Market: USA, North America
Indication(s)/use: contraception, hormone replacement
Target: Healthcare Professionals (HCP)
Tagline: Beyond birth control
[Publication: Contemporary OB/GYN June 2009

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The first OC in Canada to offer 24/4 dosing.
Discover 24/4 dosing

Drospirenone is part of certain birth control formulations. The compound differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. With its activities similar to spironolactone it may lead to less water retention and breast tenderness while improving skin appearance (less acne). Drospirenone is taken orally with about 76% bioavailability. It is bound not by sex hormone binding globulin or corticosteroid binding globulin, but by other serum proteins. Metabolites have not been shown to be biologically active, show up in urine and feces, and are essentially completely excreted within 10 days. The compound is part of certain newer oral contraceptive formulations:

* Yasmin contains 3 mg drospirenone and 30 mcg ethinylestradiol per tablet. It is indicated for the prevention of pregnancy in women who elect an oral contraceptive.
* Yasminelle contains 3 mg drospirenone and 20 mcg ethinylestradiol per tablet and is used for contraception.
* Yaz contains 3 mg drospirenone and 20 mcg ethinylestradiol per tablet and is given for 24/4 days with the same indications.

It has also been formulated in medication to manage menopausal symptoms using 0.5 mg drsp and 1 mg estradiol per day by oral application. This medication was introduced in the USA in 2007 as Angeliq. – Wikipedia

Parkhurst Exchange April 2009